The focus of my research is drug resistance. Originally focused on resistance to standard-of-care chemotherapy in colorectal cancer, this work has broadened to include mechanisms of drug resistance in multiple cancers.
The mechanism of drug resistance that I have focused on most is cell death, particularly apoptosis. My most significant achievement in this area has been identification of the apoptosis-regulating protein FLIP as a key mediator of drug resistance, a biomarker of poor prognosis and potential therapeutic target for cancer.
Open to PhD applications in the field of
Cancer biology
Cell death
Drug resistance
| PhD Title | Role of the oral commensal Fusobacterium Nucleatum in colorectal cancer. |
| Country | England |
| PhD Title | Protein-protein interactions at the Death-Inducing Signalling Complex |
| Country | England |
| Current Position | Post-doctoral researcher, QUB |
