Research Interests
Open to PhD applications in the field of
- Signal transduction and molecular cell biology
- Drug discovery targeting Gremlin1
- Human iPSC-derived 3D kidney organoids
- Gremlin1 signalling in human disease
Current Research Opportunities
- Mechanisms and models of Gremlin1 signalling in cancer and tissue fibrosis
- Development of novel small molecule inhibitors of Gremlin1, a pathogenic driver of diabetic kidney disease
- Mechanisms and models of Gremlin1 signalling in cancer and tissue fibrosis
- Development of novel small molecule inhibitors of Gremlin1, a pathogenic driver of diabetic kidney disease
Public outreach & key achievements
- Áù¾ÅÉ«Ìà Belfast Teaching Award 2020 (Student-nominated category)
- Organiser “Know Your Enemy: Disease-Focused Research at Queen’sâ€
- NI Science Festival outreach event
- Presentation at Diabetes UK Public Awareness seminars and workshops
- Visits to schools and other locations to promote careers in science and medicine
Research students
| PhD Title | Role of Suppressor of Cytokine Signalling (SOCS) proteins in the mechanisms of Mesenchymal Stem Cell therapeutic effect in Acute Respiratory Distress Syndrome |
| Country | China |
| PhD Title | Defining the signalling mechanisms of Gremlin1 in tissue fibrosis and cancer |
| Country | China |
| PhD Title | Development of novel models of kidney damage using induced human pluripotent stem cells |
| Country | UK |
Alumni: Where are they now
| PhD Title | Mechanisms and Models of Insulin Receptor Substrate-2 signalling in the kidney |
| Country | Ireland |
| Current Position | Postdoctoral Fellow, Áù¾ÅÉ«Ìà Belfast |
| PhD Title | Elucidating the mechanisms of Gremlin1-mediated Bone Morphogenetic Protein antagonism and acute kidney injury in vivo |
| Country | Northern Ireland, UK |
| Current Position | Scientist, Almac Pharmaceuticals, Craigavon, Northern Ireland |
| PhD Title | The Therapeutic Potential of Erythropoietin for ischaemic retinopathies |
| Country | Ireland |
| Current Position | Postdoctoral Fellow, Roche Pharmaceuticals, Basel, Switzerland |
Discover More
- Faculty of Medicine, Health and Life Sciences
- Wellcome-Wolfson Institute For Experimental Medicine
- Institute for Health Sciences