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We work to reconcile omics data with biological functions in the context of parasite disease control.  Our focus is on the development of novel drugs / vaccines for parasites through the discovery and validation of new targets for these interventions. 

We interrogate pathways and processes that control parasite behaviour (parasite nervous systems and muscles) as well as their growth and development (parasite stem cells) to uncover these new targets.  Vaccine candidates encompass virulence proteins involved in the host-parasite interaction as well as novel, parasite-specific proteins lacking known homologues. 

We develop functional genomics tools for parasites, facilitating the delineation of gene function and the exposure of new control targets from diverse omics datasets.  Work also encompasses the translation of in vitro gene silencing methods for both the in vivo assessment of target value and for the direct control of parasitic worms.